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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1B
All Species:
10
Human Site:
S456
Identified Species:
18.33
UniProt:
O75688
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75688
NP_002697.1
479
52643
S456
M
Q
E
S
H
T
E
S
E
S
G
L
A
E
L
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
A408
S
K
R
N
V
I
E
A
V
Y
N
R
L
N
P
Rhesus Macaque
Macaca mulatta
XP_001111662
479
52622
S456
M
Q
E
S
H
T
E
S
E
S
G
L
A
E
L
Dog
Lupus familis
XP_851683
479
52774
S456
M
Q
E
S
H
T
E
S
K
S
D
L
A
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P36993
390
42776
S368
H
V
I
E
A
V
Y
S
R
L
N
P
H
K
D
Rat
Rattus norvegicus
P35815
390
42871
S368
N
V
I
E
A
V
Y
S
R
L
N
P
N
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
A360
S
K
R
S
V
I
E
A
V
Y
N
R
L
N
P
Chicken
Gallus gallus
NP_001026223
387
42716
A365
G
K
R
N
I
I
E
A
V
Y
S
R
L
N
P
Frog
Xenopus laevis
NP_001085063
455
50420
P432
G
E
E
S
T
S
G
P
S
V
P
S
S
S
I
Zebra Danio
Brachydanio rerio
NP_001007314
382
42180
A360
S
K
R
S
V
I
E
A
V
Y
N
R
L
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
R334
N
N
F
D
G
E
Q
R
V
N
A
A
N
Q
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
N333
L
V
Q
F
K
K
P
N
P
S
E
T
E
P
E
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
D446
N
D
A
D
D
N
D
D
N
D
G
E
E
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99.5
97.2
N.A.
76.1
77
N.A.
62
77.2
78.9
67.6
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
100
71.4
100
99.1
N.A.
79.9
79.3
N.A.
70.9
79.1
86.4
74.7
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
6.6
100
86.6
N.A.
6.6
6.6
N.A.
13.3
6.6
13.3
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
13.3
13.3
N.A.
26.6
26.6
40
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
16
0
0
31
0
0
8
8
24
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
16
8
0
8
8
0
8
8
0
0
0
16
% D
% Glu:
0
8
31
16
0
8
54
0
16
0
8
8
16
24
16
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
8
0
0
0
24
0
0
0
8
% G
% His:
8
0
0
0
24
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
16
0
8
31
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
31
0
0
8
8
0
0
8
0
0
0
0
16
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
16
0
24
31
0
24
% L
% Met:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
8
0
16
0
8
0
8
8
8
39
0
16
39
0
% N
% Pro:
0
0
0
0
0
0
8
8
8
0
8
16
0
8
31
% P
% Gln:
0
24
8
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
31
0
0
0
0
8
16
0
0
31
0
0
0
% R
% Ser:
24
0
0
47
0
8
0
39
8
31
8
8
8
8
0
% S
% Thr:
0
0
0
0
8
24
0
0
0
0
0
8
0
0
0
% T
% Val:
0
24
0
0
24
16
0
0
39
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
31
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _